Acute fatty liver of pregnancy is a rare but potentially fatal complication of the third trimester of pregnancy. The exact cause of acute fatty liver of pregnancy is still debatable, and microvesicular fatty infilteration of the liver on liver
biopsy
specimens. Acute fatty liver of pregnancy should be suspected in all patients with symptoms of preeclampsia in the presence of hypoglycemia, low fibrinogen, and prolonged prothrombin time, particular in the absence of severe abruptio placenta.
Computed
tomography of the liver has a high false-negative rate in patients with acute fatty liver of pregnancy. As recently as 1980 fetal and maternal mortality rate as high as 85% were reported.With increased awareness especially in less severe cases,
the
use
of ultrasonography and computed tomography(CT) of the liver for the diagnosis of this condition, and more aggressive management, the mortality from acute fatty liver of pregnancy has been significantly reduced in the past decade. Careful
monitoring
of
input and output is necessary because of the associated renal failure, And high caloric intake of carbohydrate, vitamins, and fluid replacement is essential. Subsequent pregnancies in an appreciable number of women who previously had severe acute
fatty
liver of pregnancy have proved to be totally be(?)gn.
We have experienced a case of the acute fatty liver of pregnancy and it is reported with a brief review.
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